The driver of a semi-trailer loaded with frozen goods noticed smoke and flames coming from the rig just before 4.30 this morning and managed to pull over at Godfrey Hill Road, about 4 kilometres south of Taree.
By the time firefighters arrived, the B-Double was engulfed in flames - the driver managed to escaped uninjured.
The southbound lanes of the highway remain open but motorists are advised to expect delays.